Seahawks vs Cardinals: Odds and Betting Lines

Sportsbooks are projecting a razorthin contest between the Seahawks and Cardinals. Arizona opens slightly favored, but Seattle’s recent performances have bettors split on the outcome.







Market Line / Odds Notes
Spread Seahawks +1.5 Seattle expected to keep it close
Moneyline Seahawks +100 / Cardinals 120 Arizona favored slightly at home
Over/Under 43.5 points Many analysts leaning on the under

The narrow lines suggest that bookmakers view this as a defensive battle rather than a highscoring shootout.

Injury Report and Player Availability

Injuries are shaping the outlook for this game in a big way.

Arizona Cardinals:

  • James Conner is likely out for the season with an ankle injury.

  • Without their star running back, the Cardinals’ rushing attack becomes far less threatening.

Seattle Seahawks:

  • Robbie Ouzts and Josh Jones are dealing with ankle injuries.

  • Key contributors like Devon Witherspoon, Julian Love, Nick Emmanwori, and Zach Charbonnet remain under evaluation for availability.

The loss of Conner tilts the balance in favor of Seattle’s defensive front, which thrives when opponents are onedimensional.

Key Matchups to Watch

Seattle’s Defensive Pressure vs Kyler Murray
The Seahawks’ defensive line has generated consistent pressure through three weeks. If they can contain Kyler Murray in the pocket, Arizona’s passing game may struggle without balance.

Sam Darnold vs Arizona Secondary
Seattle quarterback Sam Darnold has looked increasingly efficient. Against Arizona’s secondary, he will need to stay turnoverfree and capitalize on shortyardage gains.

Special Teams Impact
Seattle has benefited from timely special teams plays. In a game projected to be decided by a few points, a blocked kick or return could prove decisive.

Seahawks vs Cardinals Predictions

Experts are divided, but most Seahawks vs Cardinals Predictions point toward a lowscoring game with Seattle either winning outright or covering the spread.

Bold predictions include:

  1. The Seahawks win on a late field goal.

  2. Sam Darnold posts one of his most efficient games as a starter.

  3. Kyler Murray struggles under pressure, throwing at least one interception.

  4. The total score falls below 43.5 points, consistent with defensive dominance.

Expected Game Flow

  • First Half: Arizona tries to establish tempo through Murray’s mobility, but Seattle’s defense limits explosive plays.

  • Second Half: With Conner absent, the Cardinals lean heavily on the passing game, giving Seattle’s defense more chances to create turnovers.

  • Final Moments: A narrow margin keeps fans on edge, but Seattle’s composure in lategame scenarios may give them the upper hand.

Final Score Prediction






Team Predicted Score
Seattle Seahawks 23
Arizona Cardinals 20

Seattle’s defense and special teams are the differencemakers, allowing them to edge out Arizona in a tightly contested NFC West battle.

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